ATTO Oxa12

Optical Properties
λ_abs	662	nm
ε_max	1.25×10⁵	M^-1cm^-1
λ_fl	681	nm
η_fl	30	%
τ_fl	1.8	ns
CF₂₆₀ = ε₂₆₀/ε_max	0.32
CF₂₈₀ = ε₂₈₀/ε_max	0.12

ATTO Oxa12 is a lipophilic variety of ATTO 655. Characteristic features of the label are strong absorption, good fluorescence quantum yield, excellent thermal and photo-stability, and outstanding ozone resistance. Absorption and fluorescence are pH-independent in the range pH 2 to 11, used in typical applications. ATTO Oxa12 shows excellent solubility in polar organic solvents like DMF, DMSO or acetonitrile. ATTO Oxa12 is a cationic dye. After coupling to a substrate the dye carries a net electrical charge of +1. The fluorescence is excited most efficiently in the range 640 - 675 nm. A suitable excitation source is the 647 nm line of the Krypton-Ion laser or a diode-laser emitting at 650 nm.

Documents

Product Sheets

- ATTO Oxa12 product information

- NHS-ester
- maleimide
- phalloidin
- streptavidin

Spectra

Absorption and Emission Spectrum (ASCII)

- ATTO Oxa12 absorption (.txt)

- ATTO Oxa12 emission (.txt)

Absorption and Emission Spectrum (graphic)

- ATTO Oxa12 absorption/fluorescence (.jpg)

MSDS

Material Safety Data Sheets

- ATTO Oxa12 carboxy MSDS

- ATTO Oxa12 NHS-ester MSDS

- ATTO Oxa12 maleimide MSDS

- ATTO Oxa12 streptavidin MSDS

- ATTO Oxa12 biotin MSDS

- ATTO Oxa12 phalloidin MSDS

Literature

Selected Publications for ATTO Oxa12:

C. Chen, C. Chen, Y. Li, R. Gu, X. Yan, Characterization of lipid-based nanomedicines at the single-particle level, Fundamental Research 20, 101 (2022).

N. Tiwari, E. Osorio-Blanco, A. Sonzogni, D. Esporrín-Ubieto, H. Wang, M. Calderón, Nanocarriers for Skin Applications, Angewandte Chemie International Edition 61, e202107960 (2022).

M. Qindeel, M. Ullah, Fakhar-ud-Din, N. Ahmed, A.u. Rehman, Recent trends, challenges and future outlook of transdermal drug delivery systems for rheumatoid arthritis therapy, Journal of Controlled Release 327, 595 (2020).

E. Osorio-Blanco, F. Rancan, A. Klossek, J. Nissen, L. Hoffmann, J. Bergueiro, S. Riedel, A. Vogt, E. Rühl, M. Calderón, Polyglycerol-Based Thermoresponsive Nanocapsules Induce Skin Hydration and Serve as a Skin Penetration Enhancer, ACS Applied Materials & Interfaces 12, 30136 (2020).

S. Pujals, N. Feiner-Gracia, P. Delcanale, I. Voets, L. Albertazzi, Super-resolution microscopy as a powerful tool to study complex synthetic materials, Nature Reviews Chemistry 3, 68 (2019).

A. Aloi, I. Voets, Soft matter nanoscopy, Current Opinion in Colloid & Interface Science 34, 59 (2018).

A. Gordillo-Galeano, C. Mora-Huertas, Solid lipid nanoparticles and nanostructured lipid carriers, European Journal of Pharmaceutics and Biopharmaceutics 133, 285 (2018).

P. Kokkonen, J. Sykora, Z. Prokop, A. Ghose, D. Bednar, M. Amaro, K. Beerens, S. Bidmanova, M. Slanska, J. Brezovsky, J. Damborsky, M. Hof, Molecular Gating of an Engineered Enzyme Captured in Real Time, Journal of the American Chemical Society 140, 17999 (2018).

A. Boreham, P. Volz, D. Peters, C. Keck, U. Alexiev, Determination of nanostructures and drug distribution in lipid nanoparticles by single molecule microscopy, European Journal of Pharmaceutics and Biopharmaceutics 110, 31 (2017).

A. Vogt, C. Wischke, A. Neffe, N. Ma, U. Alexiev, A. Lendlein, Nanocarriers for drug delivery into and through the skin - Do existing technologies match clinical challenges?, Journal of Controlled Release 242, 3 (2016).

P. Volz, A. Boreham, A. Wolf, T. Kim, J. Balke, J. Frombach, S. Hadam, Z. Afraz, F. Rancan, U. Blume-Peytavi, A. Vogt, U. Alexiev, Application of single molecule fluorescence microscopy to characterize the penetration of a large amphiphilic molecule in the stratum corneum of human skin, International journal of molecular sciences 16, 6960 (2015).

A. Sengupta, C. Pieper et al., Flow of a nematogen past a cylindrical micro-pillar, Soft Matter 9, 1937 (2013).

Product No.:: AD Oxa12

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